CyFlow™ CD107a APC

CD107a (LAMP-1; lysosome-associated membrane protein-1), together with CD107b (LAMP-2), is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human, Mouse, Non-Human Primate
• Antigen: CD107a
• Clone: H4A3
• Conjugate: APC
• Isotype: IgG1

• Quantity: 100 tests
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.02% (w/v) sodium azide.

• Flow Cytometry (FC)
• Immunocytochemistry (ICC)
• Immunohistochemistry (IHC)
• Western Blotting (WB)