CyFlow™ CD123 PE-Cy5

CD123 is the α chain of interleukin 3 receptor (IL-3R α). This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Antigen: CD123
• Clone: 6H6
• Conjugate: PE-Cy5
• Isotype: IgG1

• Quantity: 100 tests
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

• Flow Cytometry (FC)
• Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))
• Immunohistochemistry (Frozen Sections) (IHC (Fr))
• Immunoprecipitation (IP)
• Western Blotting (WB)