Product & ReviewsAntibodies

CyFlow™ CD14 Biotin

Product Details

Cat. No.
CV242434
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Non-Human Primate
  • Antigen: CD14
  • Clone: MEM-18
  • Conjugate: Biotin
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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