Product & ReviewsAntibodies
CyFlow™ CD140a PE
Product Details
- Cat. No.
- CA133538
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Buy Now
Receive your quote directly from the manufacturer.
Description
CD140a (PDGF-RA; platelet-derived growth factor receptor α) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b (PDGF-RB). Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD140a
- Clone: 16A1
- Conjugate: PE
- Isotype: IgG1
Handling
- Quantity: 100 tests
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)