Product & ReviewsAntibodies

CyFlow™ CD140b PE

Product Details

Cat. No.
CM847869
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD140b (PDGF-RB; platelet-derived growth factor receptor β) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a (PDGF-RA). Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumors such as medulloblastoma.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD140b
  • Clone: 18A2
  • Conjugate: PE
  • Isotype: IgG1

Handling

  • Quantity: 100 tests
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
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