Product & ReviewsAntibodies
CyFlow™ CD140b PE
Product Details
- Cat. No.
- CM847869
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD140b (PDGF-RB; platelet-derived growth factor receptor β) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a (PDGF-RA). Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumors such as medulloblastoma.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD140b
- Clone: 18A2
- Conjugate: PE
- Isotype: IgG1
Handling
- Quantity: 100 tests
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)