Product & ReviewsAntibodies

CyFlow™ CD160 PE

Product Details

Cat. No.
CL791330
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD160
  • Clone: BY55
  • Conjugate: PE
  • Isotype: IgM

Handling

  • Quantity: 100 tests
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in stabilizing Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Immunoprecipitation (IP)
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