Product & ReviewsAntibodies
CyFlow™ CD23 FITC
Product Details
- Cat. No.
- CS137840
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Buy Now
Receive your quote directly from the manufacturer.
Receive your quote directly from the manufacturer.
CD23 (Fc ε RII), the low affinity IgE receptor, is a 45 kDa type II membrane glycoprotein expressed more or less on eosinophils, follicular dendritic cells, Langerhans cells, mature B cells (mainly upon activation), EBV-transformed lymphoblasts, monocytes, and subpopulation of platelets. A soluble form of 37 kDa and other its fragments were also described. CD23 mediates IgE-dependent cytotoxicity by eosinophils and macrophages, and downregulates IgE secretion in response to high levels of IgE, involving release of pro-inflammatory cytokines.