CyFlow™ CD358 Purified

CD358 (DR6; Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Antigen: CD358
• Clone: DR-6-04-EC
• Conjugate: Purified
• Isotype: IgG1

• Quantity: 0.1 mg
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

• Flow Cytometry (FC)
• Immunocytochemistry (ICC)
• Immunoprecipitation (IP)