Product & ReviewsAntibodies
CyFlow™ CD41 PerCP
Product Details
- Cat. No.
- AA886096
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
CD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.