Product & ReviewsAntibodies

CyFlow™ CD42b FITC

Product Details

Cat. No.
AY906000
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD42b (GPIb α) composes together with GPIb β, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD42b
  • Clone: AK2
  • Conjugate: FITC
  • Isotype: IgG1

Handling

  • Quantity: 100 tests
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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