Product & ReviewsAntibodies

CyFlow™ CD44 Purified

Product Details

Cat. No.
BL322560
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumor growth and metastasis, antiapoptosis and directional motility of cancer cells.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Dog (Canine), Human, Pig (Swine)
  • Antigen: CD44
  • Clone: MEM-263
  • Conjugate: Purified
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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