Product & ReviewsAntibodies

CyFlow™ CD45R APC

Product Details

Cat. No.
BJ993887
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Sysmex Europe SE

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Description

CD45R (B220) is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Cat (Feline), Human, Mouse
  • Antigen: CD45R
  • Clone: RA3-6B2
  • Conjugate: APC
  • Isotype: IgG2a

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunocytochemistry (ICC)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
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