Product & ReviewsAntibodies
CyFlow™ CD45R Purified
Product Details
- Cat. No.
- CE555722
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
Description
CD45R (B220) is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Cat (Feline), Human, Mouse
- Antigen: CD45R
- Clone: RA3-6B2
- Conjugate: Purified
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)