CyFlow™ CD59 Biotin

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Antigen: CD59
• Clone: MEM-43
• Conjugate: Biotin
• Isotype: IgG2a

• Quantity: 0.1 mg
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

• Flow Cytometry (FC)
• Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
• Immunoprecipitation (IP)