Product & ReviewsAntibodies
CyFlow™ CD68 Purified
Product Details
- Cat. No.
- CY184980
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Description
CD68 (LAMP4, SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD68
- Clone: Y1/82A
- Conjugate: Purified
- Isotype: IgG2b
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))
- Immunohistochemistry (Frozen Sections) (IHC (Fr))