Product & ReviewsAntibodies
CyFlow™ CD84 Purified
Product Details
- Cat. No.
- BU778660
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Description
CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD84
- Clone: CD84.1.21
- Conjugate: Purified
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
- Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
Applications
- Flow Cytometry (FC)
- Functional Studies (Func)
- Immunoprecipitation (IP)