Product & ReviewsAntibodies

CyFlow™ CD85j Low Endotoxin

Product Details

Cat. No.
AG729790
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

CD85j (ILT-2; Ig-like transcript 2, LIR-1; leukocyte Ig-like receptor 1 or LILRB1; leukocyte Ig-like receptor B1) is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD85j
  • Clone: GHI/75
  • Conjugate: Low Endotoxin
  • Isotype: IgG2b

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Applications

  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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