Product & ReviewsAntibodies

CyFlow™ CD86 FITC

Product Details

Cat. No.
CQ603647
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Sysmex Europe SE

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Description

CD86 (B7-2) and CD80 (B7-1) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CD152 (CTLA-4). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD86
  • Clone: GL-1
  • Conjugate: FITC
  • Isotype: IgG2a

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunocytochemistry (ICC)
  • Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))
  • Immunoprecipitation (IP)
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