Product & ReviewsAntibodies

CyFlow™ Helios PE

Product Details

Cat. No.
CV254145
Type
Primary Antibody
Clonality
Monoclonal
Host
Hamster
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Sysmex Europe SE

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Description

Helios (IKZF2; Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.

Biological Information

  • Clonality: Monoclonal
  • Host: Hamster
  • Reactivity: Human, Mouse
  • Antigen: Helios
  • Clone: 22F6
  • Conjugate: PE
  • Isotype: IgG

Handling

  • Quantity: 100 tests
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
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