CyFlow™ HLA-DR1 (empty) PE

HLA-DR1 belongs to the HLA class II β chain paralogues. The MHC Class II molecule is a heterodimer consisting of an α (DRA) and a β chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The β chain is approximately 26-28 kDa. Within the DR molecule the β chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Antigen: HLA-DR1 (empty)
• Clone: MEM-267
• Conjugate: PE
• Isotype: IgG2b

• Quantity: 0.1 mg
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

• ELISA (ELISA)
• Flow Cytometry (FC)
• Western Blotting (WB)