Product & ReviewsAntibodies

CyFlow™ NTAL (LAB) Purified

Product Details

Cat. No.
BC100968
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse
  • Antigen: NTAL (LAB)
  • Clone: NAP-07
  • Conjugate: Purified
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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