Product & ReviewsAntibodies

CyFlow™ TCR gamma/delta Purified

Product Details

Cat. No.
BB592648
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Sysmex Europe SE

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Description

The antigen-specific T cell receptor (TCR) is composed of either α and β subunit, or γ and δ subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR α/β heterodimers, whereas the T cells expressing TCR γ/δ heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Rat
  • Antigen: TCR γ/δ
  • Clone: V65
  • Conjugate: Purified
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
  • Buffer: The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

  • Flow Cytometry (FC)
  • Functional Studies (Func)
  • Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))
  • Immunoprecipitation (IP)
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