CyFlow™ TNF-alpha APC

TNF α is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF α easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human, Non-Human Primate, Pig (Swine)
• Antigen: TNF-α
• Clone: MAb11
• Conjugate: APC
• Isotype: IgG1

• Quantity: 100 tests
• Storage: Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
• Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

• ELISA (ELISA)
• Flow Cytometry (FC)
• Functional Studies (Func)
• Immunocytochemistry (ICC)
• Immunohistochemistry (Formalin-Fixed Sections) (IHC (F))