Product & ReviewsAntibodies
Cytokeratin-4 Antibody
Product Details
- Cat. No.
- 251382
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Keratin, type II cytoskeletal 4 (cytokeratin-4) is a heterotetramer composed of two type I and two type II keratins. Cytokeratin-4 is generally associated with keratin-13. Defects in cytokeratin-4 are a cause of white sponge nevus of cannon (WSN). WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Horse (Equine), Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytokeratin-4.
- Isotype: Rabbit Ig
- Gene: P19013
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)