Product & ReviewsAntibodies
DAD1 Rabbit pAb
Product Details
- Cat. No.
- A14723
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - DAD1 antibody (A14723)
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Description
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
