Product & ReviewsAntibodies
DARPP-32 (Thr75) Antibody
Product Details
- Cat. No.
- 252532
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Protein phosphatase 1 regulatory subunit 1B (DARPP-32) is expressed in dopaminergic neurons. DARPP-32 is a dopamine and cyclic-AMP regulated phosphoprotein. DARPP-32 levels are decreased in the dorsolateral prefrontal cortex and lymphocytes of both schizophrenia and bipolar disorder patients. Phosphorylation of DARPP-32 is thought to play a critical role in the regulation of dopaminergic neurotransmission.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr75 of rat DARPP-32.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q6J4I0
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)