Product & ReviewsAntibodies
DCP2 Antibody
Product Details
- Cat. No.
- 252209
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
mRNA-decapping enzyme 2 (DCP2) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 plays a role in replication-dependent histone mRNA degradation. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. DCP2 has higher activity towards mRNAs that lack a poly(A) tail, and has no activity towards a cap structure lacking a RNA moiety.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DCP2.
- Isotype: Rabbit Ig
- Gene: Q8IU60
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)