Product & ReviewsAntibodies
DDR1 (2G4E) Antibody
Product Details
- Cat. No.
- 252798
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
DDR1 (Epithelial discoidin domain-containing receptor 1, CD167a) is a receptor tyrosine kinase involved in cell-cell interactions and recognition. It is expressed in epithelial cells especially in the kidney, lung, gastrointestinal tract, and brain, and more highly in human breast, ovarian, esophageal, and pediatric brain tumors. Types I-VI collagen all induce the autophosphorylation of DDR1. Collagen regulates the interaction of DDR1 with KIBRA (WWC1), activating MAPK; these events are involved in mammary gland development.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of DDR1(aa602-681) expressed in E. coli. <br>"
- Clone: 2G4E12
- Isotype: Mouse IgG1
- Gene: Q08345, NP_054699
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)