Product & ReviewsAntibodies
DGCR8 Antibody
Product Details
- Cat. No.
- 252193
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Microprocessor complex subunit DGCR8 (DGCR8) is a component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 functions as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away from the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of DGCR8.
- Isotype: Rabbit Ig
- Gene: Q8WYQ5
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)