Dopamine D2 Receptor Antibody
Product Details
- Cat. No.
- 251384
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
D(2) dopamine receptor (dopamine D2 receptor) is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Genetic variations in the dopamine D2 receptor are implicated in the genetic susceptibility to alcoholism. Genetic variations in the dopamine D2 receptor are a protective factor against the development of withdrawal symptoms but might also be a risk factor in a highly burdened subgroup of alcoholics with a paternal and grandpaternal history of alcoholism and might contribute to suicide risk in alcoholics.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human dopamine D2 receptor.
- Isotype: Rabbit Ig
- Gene: P14416
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)