Product & ReviewsAntibodies
DPYD Rabbit pAb
Product Details
- Cat. No.
- A1620
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - DPYD Antibody (A1620)
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Description
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
