Product & ReviewsAntibodies
DR-4 Antibody
Product Details
- Cat. No.
- 251951
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
HLA class II histocompatibility antigen, DRB1-4 beta chain (DR-4) is a heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. DR-4 binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accomodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DR-4.
- Isotype: Rabbit Ig
- Gene: P13760
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)