DSG1 Rabbit pAb
Product Details
- Cat. No.
- A9812
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - DSG1 antibody (A9812)
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Description
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Rat
