DUOX1 Rabbit pAb
Product Details
- Cat. No.
- A8583
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - DUOX1 antibody (A8583)
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Description
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
