Dynamin-1 (3G4B) Antibody
Product Details
- Cat. No.
- 252653
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Dyn1 (Dynamin-1) is a 864-amino acid protein (~95kDa) belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain and lungs), constitute the dynamin family. Members of the dynamin family are GPTases, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human Dynamin-1 expressed in E. coli.
- Clone: 3G4B6
- Isotype: Mouse IgG2a
- Gene: Q05193
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)