Product & ReviewsAntibodies
Dynamin-2 (5E4C) Antibody
Product Details
- Cat. No.
- 252686
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Dynamin-2 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-2 is involved in vesicular trafficking processes, in particular endocytosis. Defects in dynamin-2 are a cause of centronuclear myopathy autosomal dominant (ADCNM), also known as autosomal dominant myotubular myopathy. Centronuclear myopathies (CNMs) are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk and neck muscles.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of Dynamin-2 expressed in E. coli.
- Clone: 5E4C2F3
- Isotype: Mouse IgG2a
- Gene: P50570
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)