Dysbindin Antibody
Product Details
- Cat. No.
- 251283
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Dysbindin, short for dystrobrevin-binding protein 1, is a protein constituent of the dystrophin-associated protein complex (DPC) of skeletal muscle cells. It is also a part of BLOC-1, or biogenesis of lysosome-related organelles complex 1. Dysbindin is found in neural tissue of the brain, particularly in axon bundles and especially in certain axon terminals, notably mossy fiber synaptic terminals in the cerebellum and hippocampus. In humans, dysbindin is encoded by the DTNBP1 gene. An association was found between expression of a particular dysbindin allele and a clinical expression of schizophrenia.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Drosophila melanogaster
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of Drosophila dysbindin.
- Isotype: Rabbit Ig
- Gene: Q9VVT5
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)