Dystrophin Antibody
Product Details
- Cat. No.
- 251744
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Dystrophin anchors the extracellular matrix to the cytoskeleton via F-actin. Dystrophin is the ligand for dystroglycan. Dystrophin is a component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.Defects in DMD are the cause of Duchenne muscular dystrophy (DMD). DMD is the most common form of muscular dystrophy; a sex-linked recessive disorder. It typically presents in boys aged 3 to 7 year as proximal muscle weakness causing waddling gait, toe-walking, lordosis, frequent falls, and difficulty in standing up and climbing up stairs.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rabbit (Lapine), Rat
- Antigen: Recombinant human dystrophin fragment.
- Clone: MANDYS8
- Isotype: Mouse IgG2b
- Gene: P11532
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)