Product & ReviewsAntibodies
E-cadherin Antibody
Product Details
- Cat. No.
- 200134
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human E-cadherin.
- Isotype: Rabbit Ig
- Gene: P12830, NP_004351
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)