Product & ReviewsAntibodies
E2F-1 Antibody
Product Details
- Cat. No.
- 251241
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
E2F-1 (Transcription factor E2F1) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially to RB1 protein in a cell-cycle dependent manner. E2F-1 can mediate both cell proliferation and p53-dependent apoptosis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term of human E2F-1.
- Isotype: Rabbit Ig
- Gene: Q01094
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)