EB2 Antibody
Product Details
- Cat. No.
- 250128
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
EB proteins belong to the microtubule plus end tracking family proteins. They interact with cytoplasmic microtubules in interphase cells, with mitotic spindles, and with the adenomatous polyposis coli (APC) tumor suppressor. The end-binding protein 1, 2 and 3 (EB1-3) are involved in microtubule polymerization and stabilization with centrosomes as well as spindle function. The N-terminal domain of EB proteins binds to microtubules whereas the C-terminal domain forms mutually exclusive complexes with APC and DCTN1. This antibody recognizes the human, monkey, mouse and hamster EB2 in ELISA, Western blot, immunoprecipitation and immunofluorescent staining.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Monkey, Mouse
- Antigen: Purified full-length human EB2-GST fusion protein
- Clone: KT52
- Isotype: rat IgG2b
- Gene: Q15555, NP_055083
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunoprecipitation (IP)
- Western Blotting (WB)