Product & ReviewsAntibodies
ECE-1 Antibody
Product Details
- Cat. No.
- 251559
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Endothelin-converting enzyme 1 (ECE-1) is an enzyme that hydrolyzes hydrolysis the 21-Trp-|-Val-22 bond in big endothelin, thus forming endothelin 1. Defects in ECE-1 are a cause of Hirschsprung disease, cardiac defects and autonomic dysfunction (HSCRCDAD). It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ECE-1.
- Isotype: Rabbit Ig
- Gene: P42892
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)