Product & ReviewsAntibodies
EDNRB Rabbit pAb
Product Details
- Cat. No.
- A2908
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - EDNRB antibody (A2908)
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Description
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
