Product & ReviewsAntibodies
EIF2AK3 Rabbit pAb
Product Details
- Cat. No.
- A18196
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - EIF2AK3 antibody (A18196)
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Description
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
