Protein argonaute-4 (EIF2C4) is required for RNA-mediated gene silencing (RNAi). EIF2C4 binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. EIF2C4 lacks endonuclease activity and does not appear to cleave target mRNAs. EIF2C4 is also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human EIF2C4.
- Isotype: Rabbit Ig
- Gene: Q9HCK5
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)