Product & ReviewsAntibodies
ELAC2 Rabbit pAb
Product Details
- Cat. No.
- A7128
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - ELAC2 Antibody (A7128)
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Description
The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
