Product & ReviewsAntibodies
Endothelin B Receptor Antibody
Product Details
- Cat. No.
- 251852
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The endothelin receptor B (EDNRB) is a non-specific receptor for endothelin 1, 2 and 3. EDNRB mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Defects in the endothelin receptor B are a cause of Waardenburg syndrome type 4A (WS4A), also known as Waardenburg-Shah syndrome. WS4A is characterized by the association of Waardenburg features (depigmentation and deafness) and the absence of enteric ganglia in the distal part of the intestine (Hirschprung disease).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human endothelin B receptor.
- Isotype: Rabbit Ig
- Gene: P24530
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)