Product & ReviewsAntibodies

eNOS (6H2) Antibody

Product Details

Cat. No.
252928
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

eNOS (Endothelial NOS) is a nitric oxyde synthase enzyme, part of the Nitric oxyde pathway. Nitric oxide synthases (NOS) are enzymes that catalyze the generation of nitric oxide (NO) from L-arginine and require nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. At least three isioforms of NOS have been idenified: neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS). NOS-3 (eNOS, endothelial NOS) produces NO which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: Purified recombinant fragment of human eNOS expressed in E. coli.
  • Clone: 6H2
  • Isotype: Mouse IgG1
  • Gene: P29474

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
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