EphA2 (1B3C) Antibody
Product Details
- Cat. No.
- 252652
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
EphA2 (EPH receptor A2) is a 976-amino acid protein (~107 kDa) belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers. EphA2 may serves as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of EphA2 expressed in E. coli.
- Clone: 1B3C7
- Isotype: Mouse IgM
- Gene: O43921
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)