Product & ReviewsAntibodies
EphB (Tyr298) Antibody
Product Details
- Cat. No.
- 252537
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Ephrin ligands, which bind ephrin receptors, play a role in cell migration and neural crest development. Binding of ephrin ligands to the ephrin B receptor blocks the dorsolateral migration of early-migrating neural crest cells. Conversely, ephrin B receptor signaling stimulates the dorsolateral migration of melanocytes. Collectively, research has shown that ephrin ligands are involved in the appropriate trafficking of migrating cells during neuronal development. Phosphorylation of Tyr298 plays a key role in EphrinB signaling.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Tyr298 of xenopus EphrinB.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: B7ZQX6
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)